One of the goals of physical education is to improve the opportunity of student participation in physical activity and enjoy the fun of exercise, as well as develop the life long exercise habit. Multiple perspectives of innovative education and teaching methods enhance the teaching quality and learning. The purpose of this study was to investigate the learning effects of Teaching Games for Understanding (TGfU) on Korfball learning among the senior high school students. The study also aimed at examining the different learning effects among the students with different skill levels. This study used a mixed methodology to examine the learning effects of TGfU through five weeks of 10 lessons of Korfball instruction. Thirty-eight senior high school students (18 males and 20 females) volunteered to participate in this study. Pretest and posttest were administration using cognitive test, objective and subjective skill test, affective test, and Game Performance Assessment Instrument (GPAI). The quantitative data were analyzed by pair-samples t test, independent t test and ANCOVA (analysis of covariance). The qualitative data were collected by semi-structured interviews and analyzed using constant comparison method. The results were as follow: (1) There were significant learning effects on cognitive posttest (78.68>46.18), skill posttests (83.42>75.00) and game performance posttest (57.56>28.89). (2) There were significant learning effects on cognitive performance posttest (80.42>47.50) and game performance posttest (64.84>35.90) for males and cognitive performance posttest (77.13>45) and game performance posttest (50.29>21.88) for females. (3) Males performance on passing and the game performance were significantly better than females but there were no significant learning effect on cognitive, shooting skill and affective performance. (4) There were significant perceived learning effects on cognitive, skills, affective, and game performance among students with different skill levels. The study found that TGfU could improve the learning effects on Korfball for students and perceived learning effects for high and low skilled students. Research findings could be used to build a reference database of TGfU for physical education teachers and teacher education program in invasion games instruction.