The purpose of this study was to determine the effects of a prescribed exercise program implemented in a required university core fitness course on selected student health fitness parameters. There were 1,102 students registered in this Fitness for Life course, with each concurrently enrolled in one of 11 content area lectures, and one of 45 fitness activity laboratories that convened twice a week. Laboratory protocols consisted of (1) pre-post supervised activity fitness assessments that included: blood pressure, grip strength, one minute push-ups, one minute bent-knee sit-ups, 8” step test, low back flexibility, body composition via 3 site skinfold testing, and a validated cardiorespiratory test, e.g., Rockport/Walkport 1 mile walk, 1.5 mile run, 12 minute run, and (2) activity based interventions over the semester that included a variety of cardiorespiratory and resistance training activities, e.g., walking, running, machine aerobics, resistance and flexibility training. Three-hundred fifteen students volunteered to participate in the study. All subjects were required to compile pre and post testing scores, and submit their results to the investigators at the conclusion of the semester. Only 238 of the original sample completed all of the tests, and their data were retained for analysis. Pre/post testing means and standard deviations were calculated as follows: blood pressure – M = 118.82/74.25 - 115.33/71.29, ó = 13.93/9.6/ 12.46/ 9/25; grip strength – M = 76.25/78.44, ó = 22.95/23.89; push-ups – M = 33.69/39.18, ó = 12.43/15; 8” step test recovery time – M = 51.82/48.10, ó = 13.36/11.67; bent knee sit-ups – M = 47.42/52.10, ó = 16.19/17.74; sit and reach flexibility – M = 27.99/30.04, ó 12.4/12.23; skinfold body composition – M = 19.47/18.09, ó = 8.22/7.70; cardiorespiratory testing – M = 15.09/14.96, ó = 2.67/2.55. A multivariate within subjects repeated measures design was employed to evaluate the pre and post testing data. Results demonstrated significant gains (p < .001) for all pre-post test dependent variables except for the cardiorespiratory assessment. In general, the activity interventions with the exception of the cardiorespiratory contingent were effective for this student sample. It is suggested that more structure be imposed on cardiorespiratory activities in future semesters, and that the staff put forth a greater effort to impose on the students the importance of consistently monitoring their progress in health related fitness. Keyword(s): assessment, exercise/fitness/physical activity, research