For many minority and economically disadvantaged female adolescents, incidences of teen pregnancy, gang involvement, and alcohol and drug abuse are high (English et al., 2002). One approach to curtailing such negative behaviors is through increased participation in sport (Women’s Sports Foundation, 2003). Several benefits of girls’ participation in sport activities have been identified, including increased levels of confidence and body image, and decreased levels of depression, obesity, and osteoporosis (President’s Council on Physical Fitness and Sports, 1997). The purpose of this study was to determine whether the self-concept of economically disadvantaged minority females would be enhanced through their participation in the GoGirlGo (GGG) project, a sport-related curriculum created by the Women’s Sports Foundation. Seventy-six girls enrolled in the sixth and seventh grades from a charter middle school were recruited for participation in the GGG project (mean age = 11.43 years), with a significant proportion of the girls (86.8%) claiming Hispanic descent. The GoGirlGo project consisted of two one-hour sessions held each week, for five consecutive weeks, as part of the girls’ regular physical education coursework. Each session included classroom discussion and physical activities that centered on topics of stress, body image, drug use, depression, self-esteem, bullying, diversity and tolerance, dating, and the importance of a strong body-strong mind connection. A second group of girls, not exposed to the GGG curriculum, was also used as a control group in the study. These girls were identical to the GGG treatment group in terms of their age, ethnicity, socio-economic status level, and number of hours of physical education time per week. To determine the effectiveness of the GGG project in enhancing self-concept, pre- and post-test measures for both groups were collected using the Piers-Harris Children’s Self-Concept Scale-2 (Piers & Herzberg, 2002). This scale assesses the respondent’s overall self-concept, and also provides information on six specific components of self-concept. A 2 (Group) x 2 (Time) MANOVA was conducted. Results indicated a significant improvement for overall self-concept (TOT) in the GGG group (mean T-score increased from 46.74 to 49.12, p<.002), as well as increases in the specific domains of Intellectual and School Status (INT mean T-score increased from 46.70 to 49.41, p<.001) and Physical Appearance and Attributes (PHY mean T-score increased from 44.24 to 46.66, p<.006). A six-month follow-up assessment of self-concept in the GGG group revealed that these improvements in self-concept were still prevalent. No significant changes were observed in the control group.Keyword(s): middle school issues, physical activity, youth-at-risk