The purpose of this multi-case study was to provide insight into the social interaction and physical activity patterns of overweight and non-overweight children. Qualitative research methods were utilized to determine the perspectives of four children (two overweight and two non-overweight) and their parents with regard to their social interaction and physical activity patterns. The researcher conducted interviews, made participant observations in different settings, and analyzed personal documents of the participants. The researcher conducted on-going interviewing. Two types of interviewing were employed. One type of interviewing was periodic, in-depth, semi-structured interviews in the form of “guided conversations” (Lofland & Lofland, 1995). Another source of qualitative data collection was participant observation (Bogdan & Biklen, 1998). Observations occurred in many different school settings. Some of these settings included: classrooms, physical education, lunchroom, and recess. These observations took place over the period of 6 weeks. The researcher observed a minimum of three days per week and visited the subjects during different times of the school day. A third source of qualitative data collection was the assembling of personal documents from the participants. These documents came in the form of class assignments, stories, drawings, and worksheets. These documents were of particular interest and helped the researcher understand the children’s perceptions and “lived experiences” (Bogdan & Biklen, 1998). Inductive analysis and the constant comparative method were used to analyze the data. Several themes or continuing issues emerged from the in-depth interviews, informal observation interviews, observations of the participants in different settings, and personal documents created by these four children. These themes included information on children’s perceptions of overweight children, the physical activity and nutritional patterns of children, the attitudes towards physical education and physical activity, and the social interaction patterns of overweight and non-overweight children. Emerging themes were further explored in follow-up interviews conducted at the end of the observational period.