The purpose of the investigation was to evaluate an 8-week pre-season high school football conditioning program. Nineteen male volunteers participated in the periodic, multiple set strength and conditioning program. Subjects mean demographic data include: age 17.6 years, height 175.7 cm, and weight 83.9 kg. Physiologic adaptations were assessed utilizing the following methods: Wingate power test (WPT), Margaria-Kalamen test (MKT), 40-yard dash time (40YD), and vertical jump (VJ), and the core weight training exercises. The core weight training exercises included the bench press (BP) and the squat. Data (mean + SD) were analyzed by independent t-test and significance determined at the p < .001 level. RESULTS: The results indicated a significant increase for the WPT (666.4 watts,SD141.8, 759.4 watts,SD 153.1); MKT (121.8 kgm/sec,SD6.9, 127.2 kgm/sec,SD7.3); VJ (20.1 inches,SD3.4, 22.3 inches,SD3.9); BP (191.3 lbs.,SD 35.2, 220.0 lbs.,SD37.3); and Squat (301.1 lbs.,SD54.5, 367.1 lbs.,SD69.4) respectively. The 40YD (5.1 sec.,SD.03, 4.9 sec.,SD.30) significantly decreased. In conclusion, the data indicate a statistical significant change in all variables following an 8-week strength/power conditioning program. An average increase of 12% for all variable assessed with the exception of 40YD time which decrease by 4%. A comprehensive review of the strength and conditioning program and the rate of adaptation by the subjects will be included in the presentation. No injuries were documented that required any subject to restrict their training and/or withdraw from the study. The practical implications of these adaptations on athletic performance and/or injury prevention require further investigation.Keyword(s): coaching, performance, youth sports