Cardiovascular disease (CVD) is the leading cause of death in the United States. As with the overall population, it is also the leading cause of death among individuals with spinal cord injury (SCI). Epidemiological research has shown obesity to be a major risk factor for developing CVD. Obesity is prevalent in both sedentary and physically active people with SCI. Moreover, clinical concerns about the effects of obesity have been shifting from total body fat to that of fat patterning (Fp) and distribution. The ability to estimate intra-abdominal fat is of primary importance as it relates to health. Given the increased risk of disease associated with Fp, an easy and accurate method of Fp assessment is an important component of the health profile of individuals with SCI. This study focused on women with SCI. In this study, females (n = 24) with SCI, 25 to 69 years of age (M = 41.3 ± 13.3), were assessed using Dual energy x-ray absorptiometry (DXA) as the criterion measure. Eleven standardized skinfold (SF) sites were measured and analyzed with partial correlations in varying combinations and ratios to determine the best predictors to enter, along with demographic information, as possible predictors for regression analysis. An equation was developed and validated to determine relative trunk fat (%TrF). %TrF = 8.569 + (TrSs2 ) .003608 - (Ab) .205, (R2 = .89, SEE = 3.74). However, the equation was not validated. A valid clinical method of determining Fp will enable health professionals to identify clients with SCI who are at-risk for disease and document Fp changes due to exercise. These measures can also be used by medical and health professionals to monitor changes in fat distribution mass resulting from SCI. This could lead to the development of more effective nutrition and exercise intervention strategies to counteract the incidence of CVD associated with SCI. Keyword(s): assessment, measurement/evaluation, wellness/disease prevention